Hi SM. Possibly the worst thing that can happen to any dog lover is to find your pup lethargic, puking, refusing to eat or drink and pooping bloody water. This recently happened to my boys and we're still in mid-battle. Background: We bought our pups from an ad on kajiji and were given cards showing that they had their first 2 rounds of shots. (parvo included). Late August: Late Sept: Fast forward a few months and they were a bit behind on the next boosters when parvo struck. Hoser and Slacker Just before: Initial Symptoms: Slacker refused to eat a treat and seems disinterested in playing...I figured he prolly ate some bark or something in the back yard and would be fine by morning. (Hoser was totally normal). Next morning he was very lethargic, refused to drink or eat and had dry heaves....so we rushed him to the vet. Vet said the initial shots they got were useless as they were done too soon. Because there was no bloody diarrhea yet we figured he might have something stuck in his guts. Temperature was ok, blood tests were ok as were xrays....then he had explosive diarrhea in the clinic which tested positive for parvo. IV bag and into quarantine he went. Hoser was at home and remained fine but we got his parvo shot immediately. Several days in the hospital and Slacker started coming around....but now Hoser was coming down with symptoms but not puking and still had mostly solid poop, so we started him on tamiflu and pedialyte. Just as Slacker was ready to come home from hospital, Hoser was going downhill and as of this post is checked in for IV and overnight stay. At home, Slacker is currently running this treatment. 24mg Cerenia (stop puking) 5cc Sucralfate one hour prior to other meds. (fix guts) 1/2 cap 75mg Tamiflu every 12 hrs. (limit other problems while weak immune) 250 mg Metronidazole every 12 hrs. (stop diarrhea) In both cases it was caught VERY early and immediately treated. I'm quite hopeful Slacker will pull through as he is eating now and drinking on his own. I have the entire trailer floors and furniture covered in painters plastic and tarps as i'm expecting some nasty accidents. Plenty of fluids, chicken broth, bleach etc. Parvo can live for YEARS in soil or on surfaces and can ONLY be killed with BLEACH. Nothing else does it apparently. I'm very scared for Hoser as he was in pretty rough shape when we put him into quarantine a couple hours ago. Updates to follow and much sincere thanks to those who have helped with prayers. Current cost of treatment, meds, ect... Upwards of $2500 While I am generally an anti-vaccer - having seen how fast and hard this can hit your dog - it's worth making SURE your dog is up to date on this shot.